Prenatal Testing and its importance: Chromosomal abnormalities in the foetus constitute one of the leading causes of stillbirth and birth of infants with malformations.
|Trisomy 21||1 in 800 births|
|Trisomy 13||1 in 10,000 newborns|
|Trisomy 18||1 in 6,000 live births|
|Turner syndrome||1 in 2,500 live female births|
|Klinefelter syndrome||1 in 500 – 1,000 baby boys|
|Triple X||1 in 1,000 newborn girls|
Prenatal testing is important as it
PRENITA NIPT is a Non-Invasive Prenatal Screening Test (NIPT) performed on cell free DNA extracted from maternal blood. During pregnancy, DNA fragments from the baby in the amniotic fluid crosses the placenta and enters the mother’s bloodstream. PRENITA NIPT is performed on this DNA to check for genetic conditions such as presence of extra or missing chromosomes and small microdeletions that could affect the baby’s health.
PRENITA NIPT IS:
PRENITA NIPT is ideal for expectant mothers with
Conditions tested in PRENITA NIPT:
How do I arrange this test?
Follow up services offered by BioServe’s PRENITA
PRENITA NIPT is a Non-Invasive Prenatal Screening Test oered by Bioserve. It’s simple, fast, reliable, and most importantly, it’s safe! As the name suggests, it’s a non-invasive test done to rule out any genetic issues the baby might have. Our genetic system consists of DNA, of which the baby receives one set from the mother and the other set from the father. During pregnancy, bits of the baby’s DNA enter the mother’s blood. Thus, by extracting the mother’s blood, these DNA bits from the baby can be identified and tested upon.
The normal genetic chromosomal number is 46. Aneuploidy is the presence of an abnormal number of chromosomes. Microdeletion involves chromosomal deletions that include several genes in a chromosome. PRENITA NIPT screens for chromosomal aneuploidies and PRENITA NIPT MD screens for chromosomal aneuploidies and 5 common microdeletions.
Chromosomal aneuploidies screened:
The prime concern for a mother is that her child be born without any complications. NIPT tests help in doing just that. Though not necessary, these tests help clear any chance of doubt that an expecting parent might have. With close to 99% accuracy at as early as 10 weeks into gestation, these tests provide vital clues about any concerns that may arise.
NIPT is a screening test that provides a checklist and score card to the above mentioned genetic conditions (aneuploidy and microdeletion ). An indication of Low Risk or High Risk helps you to determine the next line of action to assess your baby’s condition. This may include further tests to examine and determine the issue.
NIPT does not screen for certain defects like open neural tube defects and cannot predict late pregnancy complications like pre-eclampsia. Thus, maternal serum screening or ultrasound cannot be avoided.
Down Syndrome is a condition wherein there is an extra set of chromosomes (3 copies of chromosome 21 instead of 2 copies) in the child. This kind of aneuploidy is a result of random errors during DNA replication, either at conception or during the initial stages of pregnancy. It is not an inherited genetic condition and thus cannot aect the second child.
It is a screening test and not a diagnostic test, and chromosomal abnormalities such as unbalanced translocations, deletions, and duplications cannot be detected by NIPT.
If the NIPT test reveals a High-Risk score, confirmatory testing on invasive samples (CVS and amniotic fluid) must be performed. Diagnostic tests like Microarray, QFPCR, and MLPA are also offered under PRENITA as follow-ups for NIPT.
Furthermore, we care about the overall wellbeing of an expectant mother, and thus provide personalized counseling for the mother to discuss results and its impacts on her baby. An expert team of dedicated counselors ensures that every doubt is cleared and help is provided.